Jun 2020 Morphological Evidence for an Oral Venom System in Caecilian Amphibians

Abr 2020 Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI)

Jan 2020 Bufotenine, a tryptophan-derived alkaloid, suppresses the symptoms and increases the survival rate of rabies-infected mice: the development of a pharmacological approach for rabies treatment

Dez 2019 Variations in tetrodotoxin levels in populations of Taricha granulosa are expressed in the morphology of their cutaneous glands.

Out 2019 Screening of Brazilian marine animals extracts on tumor cell line panel.

Out 2019 Prospection of the antiviral effect of bufotenine on the rabies virus infection inhibition 

Out 2019 Biochemical and biological characterization of the Hypanus americanus mucus: A perspective on stingray immunity and toxins.

Set 2019 Proteomic analysis of soluble proteins retrieved from Duttaphrynus melanostictus skin secretion by IEx-batch sample preparation.

Ago 2019 Proteomic informed by transcriptomic for salivary glands components of the camel tick Hyalomma dromedarii.

Jun 2019 Unveiling toxicological aspects of venom from the Aesculapian False Coral Snake Erythrolamprus aesculapii.

Fev 2019  The Amphibian Diacylglycerol O-acyltransferase 2 (DGAT2): a 'paleo-protein' with Conserved Function but Unique Folding.

 

Fev 2019  Biochemical composition and inflammatory activity of mucus from Hypanus americanus (Dasyatis americana) marine stingray

Fev 2019  Preclinical evaluation of Amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity.

Fev 2019  Antiproliferative and antiangiogenic effect of Amblyomma sculptum (Acari: Ixodidae) crude saliva in endothelial cells in vitro.

Fev 2019  Understanding toxicological implications of accidents with caterpillars Megalopyge lanata and Podalia orsilochus (Lepidoptera: Megalopygidae)

Fev 2019  Biodistribution and Pharmacokinetics of Amblyomin-X, a Novel Antitumour Protein Drug in Healthy Mice.

Nov 2018  Morphological and biochemical characterization of the cutaneous poison glands in toads (Rhinella marina group) from different environments.

 

Mai 2018  Biological Effects and Biodistribution of Bufotenine on Mice.

 

Abr 2018  Co-Localization of Crotamine with Internal Membranes and Accentuated Accumulation in Tumor Cells.

 

Mar 2018  Synthesis of a Tyr-Tyr Dipeptide Library and Evaluation Against Tumor Cells.

 

Fev 2018  Skin gland concentrations adapted to different evolutionary pressures in the head and posterior regions of the caecilian Siphonops annulatus.

 

Out 2017  The modular nature of bradykinin-potentiating peptides isolated from snake venoms.

 

Out 2017  Preliminary molecular characterization of a proinflammatory and nociceptive molecule from the Echinometra lucunter spines extracts.

 

Ago 2017  Stinging caterpillars from the genera Podalia, Leucanella and Lonomia in Misiones, Argentina: A preliminary comparative approach to understand their toxicity.

 

Jun 2017  Isolation and biochemical characterization of bradykinin-potentiating peptides from Bitis gabonica rhinoceros.

 

Mai 2017  Venomics analyses of the skin secretion of Dermatonotus muelleri: Preliminary proteomic and metabolomic profiling.

 

Abr 2017  Parotoid, radial, and tibial macroglands of the frog Odontophrynus cultripes: Differences and similarities with toads.

 

Jan 2017  An unexpected cell-penetrating peptide from Bothrops jararaca venom identified through a novel size exclusion chromatography screening.

 

Nov 2016  The cutaneous secretion of the casque-headed tree frog Corythomantis greeningi: Biochemical characterization and some biological effects.

 

Out 2016  Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo.

 

Set 2016  The urticating apparatus in the caterpillar of Lonomia obliqua (Lepidoptera: Saturniidae).

 

Mai 2016  Initial peptidomic profiling of Brazilian sea urchins: Arbacia lixula, Lytechinus variegatus and Echinometra lucunter.

 

Abr 2016  Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell.

 

Jan 2016  Specific role of cytoplasmic dynein in the mechanism of action of an antitumor molecule, Amblyomin-X.

 

Dez 2015  Synergic effects between ocellatin-F1 and bufotenine on the inhibition of BHK-21 cellular infection by the rabies virus.

 

Dez 2015  Proteomic analysis of the rare Uracoan rattlesnake Crotalus vegrandis venom: Evidence of a broad arsenal of toxins.

 

Out 2015  Anuran skin and basking behavior: The case of the treefrog Bokermannohyla alvarengai (Bokermann, 1956).

 

Dez 2015 Venomics of the Australian eastern brown snake (Pseudonaja textilis): Detection of new venom proteins and splicing variants.

 

Jan 2015  Pipa carvalhoi skin secretion profiling: absence of peptides and identification of kynurenic acid as the major constitutive component.

 

Dez 2014  Dynein function and protein clearance changes in tumor cells induced by a Kunitz-type molecule, Amblyomin-X.

 

Out 2014  Bufotenine is able to block rabies virus infection in BHK-21 cells.

 

Fev 2014  Passive and active defense in toads: the parotoid macroglands in Rhinella marina and Rhaebo guttatus.

 

Mar 2014  Echinometrin: a novel mast cell degranulating peptide from the coelomic liquid of Echinometra lucunter sea urchin.

 

Dez 2013  Cathepsin B/X is secreted by Echinometra lucunter sea urchin spines, a structure rich in granular cells and toxins.

 

Apr 2013  Differences and similarities among parotoid macrogland secretions in South American toads: a preliminary biochemical delineation.

 

Fev 2013  α -RgIB: A Novel Antagonist Peptide of Neuronal Acetylcholine Receptor Isolated from Conus regius Venom.

 

Mar 2012  Skin glands, poison and mimicry in dendrobatid and leptodactylid amphibians.

 

Mar 2011  Pro-inflammatory effects of the aqueous extract of Echinometra lucunter sea urchin spines.

 

Ago 2010  Identification of a novel melittin isoform from Africanized Apis mellifera venom.

 

Set 2010  Africanized honey bee (Apis mellifera) venom profiling: Seasonal variation of melittin and phospholipase A(2) levels.

 

Fev 2010  Bradykinin-related peptides in the venom of the solitary wasp Cyphononyx fulvognathus.

 

Mar 2007  Isolation and characterization of a novel bradykinin potentiating peptide (BPP) from the skin secretion of Phyllomedusa hypochondrialis.

Publicações Acadêmicas
Patentes

Jul 2019 Fluorescent compound coupled to a carrier peptide, production process and use thereof. WIPO

Jul 2019 Fluorescent compound, production method and related use. WIPO

Jan 2018   Composto fluorescente acoplado a um peptídeo carreador, processo de produção e seu uso. INPI

Dez 2017   Composto fluorescente, processo de produção e seu uso. INPI
 

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