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Publicações científicas do grupo (últimos anos)

2024

Tubastrine, an antioxidant molecule from Tubastraea tagusensis sun coral, in the reversion of oxidative stress and neuron's death induced by Aβ42

Isolation of an antioxidant naphthoquinone from coelomic fluid of the Antarctic Sterechinus neumayery sea urchin

 

Autophagy-lysosomal pathway impairment and cathepsin dysregulation in Alzheimer’s disease

Potential use of quercetin in the reduction of craving in cocaine-dependent patients-A pilot clinical trial

2023

Design, in silico and pharmacological evaluation of a peptide inhibitor of BACE-1. 
 

Spatial Distribution and Biochemical Characterization of Serine Peptidase Inhibitors in the Venom of the Brazilian Sea Anemone Anthopleura cascaia Using Mass Spectrometry Imaging. 


Flavonoids: the use in mental health and related diseases. 


Preliminary analysis of a clinical trial of children with autism spectrum disorder treated with DHA-rich marine Schizochytrium sp. oil and multi-vitamin/mineral complex. 


Echinometra lucunter molecules reduce Aβ42- induced neurotoxicity in SH-SY5Y neuronlike cells: effects on disaggregation and oxidative stress. 


A new BACE-1 inhibitor peptide from Macrorhynchia philippina.

2022

A new therapeutic approach for bone metastasis in colorectal cancer: intratumoral melittin. 


Reproductive behaviour, cutaneous morphology, and skin secretion analysis in the anuran Dermatonotus muelleri. 
 

Biochemical and Toxinological Characterization of Venom from Macrorhynchia philippina (Cnidaria, Hydrozoa). 
 

Caspase-1 and Cathepsin B Inhibitors from Marine Invertebrates, Aiming at a Reduction in Neuroinflammation.

2021

Antioxidant and anti-sickling activity of glucal-based triazoles compounds - an in vitro and in silico study. 


Box Jellyfish (Cnidaria, Cubozoa) Extract Increases Neuron's Connection: A Possible Neuroprotector Effect. 


Quantity - but not diversity - of secreted peptides and proteins increases with age in the tree frog Pithecopus nordestinus. 


Effects of Kynurenic Acid on the Rat Aorta Ischemia-Reperfusion Model: Pharmacological Characterization and Proteomic Profiling. 


Neurotoxicity of Olindias sambaquiensis and Chiropsalmus quadrumanus extracts in sympathetic nervous system. 


Proteomic characterization of Naja mandalayensis venom. 
 

Neglected Venomous Animals and Toxins: Underrated Biotechnological Tools in Drug Development. 


Screening of new BACE-1 inhibitors from marine animals: Molecular interaction and pharmacokinetic studies to find new drug prototypes. 

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